Thera Phragma

Thera Phragma is a neuroscience biotechnology company aiming to discover and develop novel therapeutics to treat neurological disorders and neurodegenerative diseases by restoring the blood-brain barrier (BBB) integrity. The BBB is responsible for the healthy function of the central nervous system (CNS) and acts as a crucial checkpoint of essential components for maintaining homeostasis.

Dysfunction of the BBB can lead to an imbalance of essential components or an accumulation of toxic molecules resulting in the progression of the aforementioned pathologies. In the present landscape, drug discovery is focused on developing therapeutics that target specific molecular components responsible for each disease model that more often than not come across crucial obstacles including but not limited to CNS-penetration efficacy or organ specificity. In contrast, our company is committed to developing a unique and unequalled CNS-shuttling platform that will monitor movement of infiltrating damaging molecules or act to promote successful delivery of CNS-penetrant therapies via regulation of the BBB.

Our strategy is to take a broader approach in which our platform technology will promote the healthy function of the BBB and therefore address several disease areas including stroke, multiple sclerosis, Alzheimer’s disease and epilepsy amongst others as well as tackle current challenges encountered by others.


Spyros Papapetropoulos, MD, PhD

(+30) 210 8180236

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Evangelia Gralista

Web Design Internship

Evangelia Gralista from Trikala,Greece is in her senior year at University of Patras in the department of mathematics. She is currently working as a web design intern at Patras Science Park (PSP).

Vicky Tomara

Development Director

Vicky studied Business Administration at Athens University of Economics and Business and she got a M.B.A. from University of Patras. Her experience and background focus on supporting businesses-academia partnerships. Especially, she has been primarily activated in innovation supporting tools, while she worked in the past as an economist and research project manager in the industry. She has a good knowledge of the Greek innovation ecosystem actors, including academia, research institutes, regional and central governmental organizations, entrepreneurs and industry. She contributed to the launch and development of the Innovation and Technology Transfer Office of the University of Patras where she served as a Technology Transfer Consultant for 4 years. She acted as the principal organizational officer on behalf of the University of Patras for the 1st, 2nd and 3rd Patras IQ Innovation Exhibition. Also, she contributed to the launch and development of the Technology Transfer Office of Patras Science Park and she involved in the building of the collaborative network between both CERN procurement and CERN Technology Transfer Group with the Greek start up community & enterprises. She is currently the Development Director in Patras Science Park, she is member of the Advisory Board of the Proof of Concept and she participates in the selection committee in various regional innovation competitions.